BDBM16196 4-(3-Bromo-4-chlorophenyl)-1H-imidazole-5-carboxamide::Imidazole 8c

SMILES NC(=O)c1[nH]cnc1-c1ccc(Cl)c(Br)c1

InChI Key InChIKey=IRCCCXMUSJGSMV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16196   

TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
Bar-Ilan University

LigandPNGBDBM16196(4-(3-Bromo-4-chlorophenyl)-1H-imidazole-5-carboxam...)
Affinity DataIC50:  9.90E+3nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [600-1159,L699I,K702N,C879S](Human immunodeficiency virus type 1)
Bar-Ilan University

LigandPNGBDBM16196(4-(3-Bromo-4-chlorophenyl)-1H-imidazole-5-carboxam...)
Affinity DataIC50:  1.98E+4nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1159,Y780C]/Imidazoleglycerol-phosphate dehydratase [600-1029,Y780C](Human immunodeficiency virus type 1)
Bar-Ilan University

LigandPNGBDBM16196(4-(3-Bromo-4-chlorophenyl)-1H-imidazole-5-carboxam...)
Affinity DataIC50:  2.64E+4nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed