BDBM16221 (2S)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine::4-{4-[(1S)-1-(4-chlorophenyl)propyl]phenyl}-1H-pyrazole::pyrazole-based inhibitor 8b

SMILES NC[C@H](c1ccc(Cl)cc1)c1ccc(cc1)-c1cn[nH]c1

InChI Key InChIKey=HWVGILTYGZFGLR-KRWDZBQOSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16221   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Astex

LigandPNGBDBM16221((2S)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phen...)
Affinity DataIC50:  280nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed