BDBM16226 2-[4-(9H-purin-6-yl)phenyl]ethan-1-amine::2-[4-(9H-purin-6-yl)phenyl]ethanamine::6-phenylpurine compound 10

SMILES: NCCc1ccc(cc1)-c1ncnc2nc[nH]c12

InChI Key: InChIKey=AOXVRIHLGDJGQV-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT2 (Homo sapiens (Human))	BDBM16226 (2-[4-(9H-purin-6-yl)phenyl]ethan-1-amine | 2-[4-(9...) Show SMILES NCCc1ccc(cc1)-c1ncnc2nc[nH]c12 Show InChI InChI=1S/C13H13N5/c14-6-5-9-1-3-10(4-2-9)11-12-13(17-7-15-11)18-8-16-12/h1-4,7-8H,5-6,14H2,(H,15,16,17,18)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	7.2	22
Astex					Assay Description The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...				J Med Chem 50: 2289-92 (2007) Article DOI: 10.1021/jm0700924 BindingDB Entry DOI: 10.7270/Q2M32T1C
					More data for this Ligand-Target Pair