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BDBM16229 2-phenyl-1-[4-(9H-purin-6-yl)phenyl]ethan-1-amine::2-phenyl-1-[4-(9H-purin-6-yl)phenyl]ethanamine::6-phenylpurine compound 14

SMILES: NC(Cc1ccccc1)c1ccc(cc1)-c1ncnc2nc[nH]c12

InChI Key: InChIKey=HJFKANRRGGLIMD-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16229   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-Dependent Protein Kinase (PKA)


(Bos taurus (bovine))
BDBM16229
PNG
(2-phenyl-1-[4-(9H-purin-6-yl)phenyl]ethan-1-amine ...)
Show SMILES NC(Cc1ccccc1)c1ccc(cc1)-c1ncnc2nc[nH]c12
Show InChI InChI=1S/C19H17N5/c20-16(10-13-4-2-1-3-5-13)14-6-8-15(9-7-14)17-18-19(23-11-21-17)24-12-22-18/h1-9,11-12,16H,10,20H2,(H,21,22,23,24)
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PC sid
UniChem

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Similars

Article
PubMed
n/an/a 610n/an/an/an/a7.222



Astex



Assay Description
The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...


J Med Chem 50: 2289-92 (2007)


Article DOI: 10.1021/jm0700924
BindingDB Entry DOI: 10.7270/Q2M32T1C
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT2


(Homo sapiens (Human))
BDBM16229
PNG
(2-phenyl-1-[4-(9H-purin-6-yl)phenyl]ethan-1-amine ...)
Show SMILES NC(Cc1ccccc1)c1ccc(cc1)-c1ncnc2nc[nH]c12
Show InChI InChI=1S/C19H17N5/c20-16(10-13-4-2-1-3-5-13)14-6-8-15(9-7-14)17-18-19(23-11-21-17)24-12-22-18/h1-9,11-12,16H,10,20H2,(H,21,22,23,24)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 430n/an/an/an/a7.222



Astex



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


J Med Chem 50: 2289-92 (2007)


Article DOI: 10.1021/jm0700924
BindingDB Entry DOI: 10.7270/Q2M32T1C
More data for this
Ligand-Target Pair