BDBM162318 US10307427, Compound 9::US9051313, 9

SMILES O=C(Nc1csc(n1)-c1nncn1C1CC1)c1cc(c(cn1)N1CCCC1)-n1cnc(c1)C1CC1

InChI Key InChIKey=XBRXHRRXQWRKBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162318   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162318(US10307427, Compound 9 | US9051313, 9)
Affinity DataIC50:  1.90nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162318(US10307427, Compound 9 | US9051313, 9)
Affinity DataIC50:  1.90nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent