BDBM162357 US9669028, 139 (6-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazin-2-yl)(4-methylpiperazin-1-yl)methanone

SMILES CN1CCN(CC1)C(=O)c1cncc(n1)-c1cnc2[nH]ccc2c1

InChI Key InChIKey=YDJDNOFJTUFNPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162357   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM162357(US9669028, 139 (6-(1H-pyrrolo[2,3-b]pyridin-5-yl)p...)
Affinity DataIC50: >1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM162357(US9669028, 139 (6-(1H-pyrrolo[2,3-b]pyridin-5-yl)p...)
Affinity DataIC50: >1.00E+3nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent