BDBM163020 US9056865, A-147

SMILES Cc1ccc(nc1)-c1nc(ccc1Cl)N1CCN(CC1)C(=O)CCS(C)(=O)=O

InChI Key InChIKey=AJKBDTUEJZYFPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163020   

TargetSmoothened homolog(Human)
Pfizer

US Patent
LigandPNGBDBM163020(US9056865, A-147)
Affinity DataIC50:  22.5nMT: 25°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent