BDBM16343 4-(2,6-difluorophenyl)-5-[3-(propan-2-yl)-[1,2,4]triazolo[3,4-a]pyridin-6-yl]-1,3-oxazole::triazolopyridine oxazole inhibitor 13

SMILES CC(C)c1nnc2ccc(cn12)-c1ocnc1-c1c(F)cccc1F

InChI Key InChIKey=VXRMIEYRPJSGLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16343   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16343(4-(2,6-difluorophenyl)-5-[3-(propan-2-yl)-[1,2,4]t...)
Affinity DataIC50:  14.6nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed