BDBM163526 US9688615, 1

SMILES FC(F)(F)c1cc(c2nc(CC3CNC3)[nH]c2c1)C(F)(F)F

InChI Key InChIKey=QFCUYPXSZRMBEH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 163526   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163526(US9688615, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163526(US9688615, 1)
Affinity DataIC50:  6.38E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163526(US9688615, 1)
Affinity DataIC50:  60nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163526(US9688615, 1)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163526(US9688615, 1)
Affinity DataIC50:  1.98E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163526(US9688615, 1)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163526(US9688615, 1)
Affinity DataIC50:  4.24E+3nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163526(US9688615, 1)
Affinity DataIC50:  7.26E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent