BDBM163549 US9688615, 3

SMILES CC(C)(C)NC(=O)Cn1c(CC2CNC2)nc2c(cc(cc12)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=VILKBDDCFPGISP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 163549   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163549(US9688615, 3)
Affinity DataIC50: >1.00E+4nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163549(US9688615, 3)
Affinity DataIC50: >1.00E+4nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163549(US9688615, 3)
Affinity DataIC50:  900nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163549(US9688615, 3)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163549(US9688615, 3)
Affinity DataIC50:  670nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163549(US9688615, 3)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM163549(US9688615, 3)
Affinity DataIC50:  1.85E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent