BDBM163601 US9687479, 366 3-1-[(2-methoxyphenyl)carbonyl]-5-(methylsulfanyl)-1H-1,2,4-triazol-3-ylpyridine

SMILES COc1ccccc1C(=O)n1nc(nc1SC)-c1cccnc1

InChI Key InChIKey=BQULIDBUUVETFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163601   

TargetPlasma kallikrein(Homo sapiens (Human))
Verseon

US Patent
LigandPNGBDBM163601(US9687479, 366 3-1-[(2-methoxyphenyl)carbonyl]-5-(...)
Affinity DataIC50:  5.50E+3nMpH: 7.4 T: 2°CAssay Description:Human KLKB1 protein was obtained from Enzyme Research Labs. The chromogenic substrate S-2302 was obtained from DiaPharma. KLKB1 was assayed in buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKallikrein-1(Homo sapiens (Human))
Verseon

US Patent
LigandPNGBDBM163601(US9687479, 366 3-1-[(2-methoxyphenyl)carbonyl]-5-(...)
Affinity DataIC50:  5.50E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant human tissue kallikrein (KLK1) was obtained from R&D Systems. Pro-Phe-Arg-AMC (I-1295) substrate was obtained from Bachem. KLK1 enzyme is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent