BDBM163630 SR-3367::US10807944, Compound RLS2-284::US11731934, Compound RLS2-284

SMILES CCCCCCNNC(=O)c1ccc(Br)cc1

InChI Key InChIKey=YQIPSZXUSOVGKH-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 163630   

TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University Of Florida College Of Medicine

LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  1.03E+4nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University Of Florida College Of Medicine

LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  1.61E+4nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University Of Florida College Of Medicine

LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  2.00E+4nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Florida College Of Medicine

LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  3.91E+4nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  2.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  1.61E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  2.00E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  1.03E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  1.61E+4nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163630(SR-3367 | US10807944, Compound RLS2-284 | US117319...)
Affinity DataIC50:  1.03E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent