BDBM16387 4-{6-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-[1,2,4]triazolo[3,4-a]pyridin-3-yl}morpholine::triazolopyridine oxazole inhibitor 58

SMILES Fc1ccc(cc1)-c1ncoc1-c1ccc2nnc(N3CCOCC3)n2c1

InChI Key InChIKey=LMYKNINLHCJDHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16387   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16387(4-{6-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-[1,2,4]t...)
Affinity DataIC50:  11.8nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed