BDBM16401 5-[3-(1-methylcyclopropyl)-[1,2,4]triazolo[3,4-a]pyridin-6-yl]-4-(2,4,5-trifluorophenyl)-1,3-oxazole::triazolopyridine oxazole inhibitor 72

SMILES CC1(CC1)c1nnc2ccc(cn12)-c1ocnc1-c1cc(F)c(F)cc1F

InChI Key InChIKey=JOHOCXWBNVWZSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16401   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16401(5-[3-(1-methylcyclopropyl)-[1,2,4]triazolo[3,4-a]p...)
Affinity DataIC50:  2.30nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed