BDBM164104 US9687479, 384 N-[(5-chlorothiophen-2-yl)methyl]-1-[(2,4-dimethoxyphenyl)carbonyl]-3-(oxan-4-yl)-1H-1,2,4-triazol-5-amine
SMILES COc1ccc(C(=O)n2nc(nc2NCc2ccc(Cl)s2)C2CCOCC2)c(OC)c1
InChI Key InChIKey=KVIQDQUIYIPWCU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 164104
Affinity DataIC50: 550nMpH: 7.4 T: 2°CAssay Description:Human KLKB1 protein was obtained from Enzyme Research Labs. The chromogenic substrate S-2302 was obtained from DiaPharma. KLKB1 was assayed in buffer...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant human tissue kallikrein (KLK1) was obtained from R&D Systems. Pro-Phe-Arg-AMC (I-1295) substrate was obtained from Bachem. KLK1 enzyme is...More data for this Ligand-Target Pair