BDBM164309 US9669029, 49 8-Methoxy-2-{(E)-2-[1-methyl-4-(4-methyl-thiophen-3-yl)-1H-imidazol-2-yl]-vinyl}-[1,2,4]triazolo[1,5-a]pyridine
SMILES COC1=CC=CN2N=C(NC12)\C=C/c1nc(cn1C)-c1cscc1C
InChI Key InChIKey=WRJLYRXISSOTSA-SREVYHEPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 164309
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 55nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair