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BDBM16437 2-{3-[(2-hydroxyethyl)sulfanyl]-2,5-dioxopyrrolidin-1-yl}acetic acid::beta-Mercaptoethanol , N-glycylthiosuccinimide

SMILES: OCCSC1CC(=O)N(CC(O)=O)C1=O

InChI Key: InChIKey=MDGKXINAZILHDD-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16437   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase (AR)


(Homo sapiens (Human))
BDBM16437
PNG
(2-{3-[(2-hydroxyethyl)sulfanyl]-2,5-dioxopyrrolidi...)
Show SMILES OCCSC1CC(=O)N(CC(O)=O)C1=O
Show InChI InChI=1S/C8H11NO5S/c10-1-2-15-5-3-6(11)9(8(5)14)4-7(12)13/h5,10H,1-4H2,(H,12,13)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
8.10E+3n/an/an/an/an/an/an/an/a



Medical College of Wiscosin



Assay Description
The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...


Bioorg Chem 34: 424-44 (2006)


Article DOI: 10.1016/j.bioorg.2006.09.004
BindingDB Entry DOI: 10.7270/Q2SN076W
More data for this
Ligand-Target Pair