BDBM16450 6-[(2-chloro-4-fluorobenzene)sulfonyl]-2,3-dihydropyridazin-3-one::6-phenylsulfonylpyridazin-2H-3-one, 12::Phenyl-Substituted Sulfonylpyridazinone, 8s

SMILES Fc1ccc(c(Cl)c1)S(=O)(=O)c1ccc(=O)[nH]n1

InChI Key InChIKey=AFMMZMYEGLGTBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16450   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16450(6-[(2-chloro-4-fluorobenzene)sulfonyl]-2,3-dihydro...)
Affinity DataIC50:  280nMpH: 7.0 T: 2°CAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16450(6-[(2-chloro-4-fluorobenzene)sulfonyl]-2,3-dihydro...)
Affinity DataIC50:  280nMpH: 7.0 T: 2°CAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed