BDBM16621 6-{[(3-chloro-2-fluorophenyl)methane]sulfonyl}-2,3-dihydropyridazin-3-one::Benzyl-Substituted Sulfonylpyridazinone, 15j

SMILES Fc1c(Cl)cccc1CS(=O)(=O)c1ccc(=O)[nH]n1

InChI Key InChIKey=SUPFWUJUZJBSEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16621   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16621(6-{[(3-chloro-2-fluorophenyl)methane]sulfonyl}-2,3...)
Affinity DataIC50:  54nMAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed