BDBM16663 N-(4-{[2-(4-sulfamoylphenyl)ethyl]sulfamoyl}phenyl)acetamide::aromatic sulfonamide compound 28

SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=TXQNFGSNONKCOR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 16663   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM16663(N-(4-{[2-(4-sulfamoylphenyl)ethyl]sulfamoyl}phenyl...)
Affinity DataKi:  75nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Mus musculus (mouse))
Universita Degli Studi Di Firenze

LigandPNGBDBM16663(N-(4-{[2-(4-sulfamoylphenyl)ethyl]sulfamoyl}phenyl...)
Affinity DataKi:  103nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universita Degli Studi Di Firenze

LigandPNGBDBM16663(N-(4-{[2-(4-sulfamoylphenyl)ethyl]sulfamoyl}phenyl...)
Affinity DataKi:  119nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM16663(N-(4-{[2-(4-sulfamoylphenyl)ethyl]sulfamoyl}phenyl...)
Affinity DataKi:  187nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed