BDBM16674 N-[(2S)-1-(3,5-difluorophenyl)-3-hydroxypropan-2-yl]-2-({[(1S,2S)-2-methylcyclopropyl]methyl}amino)-6-(N-methylmethanesulfonamido)pyridine-4-carboxamide::isonicotinamide, 13

SMILES C[C@H]1C[C@@H]1CNc1cc(cc(n1)N(C)S(C)(=O)=O)C(=O)N[C@H](CO)Cc1cc(F)cc(F)c1

InChI Key InChIKey=WOZUPVNRNGMNND-CRFBAAHOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16674   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16674(N-[(2S)-1-(3,5-difluorophenyl)-3-hydroxypropan-2-y...)
Affinity DataIC50:  74nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed