BDBM167416 US9073893, 9
SMILES Cn1n(C2CCNCC2)c(=O)c2c(cccc12)C(N)=O
InChI Key InChIKey=XCMZWTDSYWVLET-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 167416
Affinity DataKd: 14nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
Affinity DataKd: 140nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair