BDBM167965 1-(2-Methyl-1H-imidazol-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3u)

SMILES Cc1nccn1CC(O)COc1ncnc2ccccc12

InChI Key InChIKey=XTCMHHNUPIPYQB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 167965   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167965(1-(2-Methyl-1H-imidazol-1-yl)-3-(quinazolin-4-ylox...)
Affinity DataIC50:  55.7nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167965(1-(2-Methyl-1H-imidazol-1-yl)-3-(quinazolin-4-ylox...)
Affinity DataIC50:  266nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167965(1-(2-Methyl-1H-imidazol-1-yl)-3-(quinazolin-4-ylox...)
Affinity DataIC50:  586nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167965(1-(2-Methyl-1H-imidazol-1-yl)-3-(quinazolin-4-ylox...)
Affinity DataIC50:  444nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed