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BDBM168004 US9073926, 38

SMILES: Cc1ccnc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)c1

InChI Key: InChIKey=JKXDDXLLFULDSB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168004   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (human))
BDBM168004
PNG
(US9073926, 38)
Show SMILES Cc1ccnc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)c1
Show InChI InChI=1S/C18H17N5O2/c1-11-5-7-19-15(9-11)22-17(24)13-4-3-12-10-14-18(25)20-6-2-8-23(14)16(12)21-13/h3-5,7,9-10H,2,6,8H2,1H3,(H,20,25)(H,19,22,24)
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MMDB

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PC sid
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Similars

n/an/a 3.80n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair