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BDBM168012 US9073926, 46

SMILES: CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccccc2)c1

InChI Key: InChIKey=VHYKGAUCYCNUBF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168012   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (human))
BDBM168012
PNG
(US9073926, 46)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccccc2)c1
Show InChI InChI=1S/C23H22N6O2/c1-15-9-10-24-23(31)20-11-17-7-8-19(27-21(17)29(15)20)22(30)26-18-12-25-28(14-18)13-16-5-3-2-4-6-16/h2-8,11-12,14-15H,9-10,13H2,1H3,(H,24,31)(H,26,30)
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MMDB

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PC sid
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Similars

n/an/a 0.390n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair