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BDBM168033 US9073926, 67

SMILES: Clc1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4n3)nc2c1

InChI Key: InChIKey=ULXCPSCTMQCILD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168033   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (human))
BDBM168033
PNG
(US9073926, 67)
Show SMILES Clc1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4n3)nc2c1
Show InChI InChI=1S/C19H15ClN6O2/c20-11-3-5-12-14(9-11)24-19(23-12)25-17(27)13-4-2-10-8-15-18(28)21-6-1-7-26(15)16(10)22-13/h2-5,8-9H,1,6-7H2,(H,21,28)(H2,23,24,25,27)
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MMDB

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PC cid
PC sid
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Similars

n/an/a 6.10n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair