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BDBM168045 US9073926, 79

SMILES: CC(C)(C)c1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)no1

InChI Key: InChIKey=ZMEYPNTUCZBQQN-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168045   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168045
PNG
(US9073926, 79)
Show SMILES CC(C)(C)c1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)no1
Show InChI InChI=1S/C19H21N5O3/c1-19(2,3)14-10-15(23-27-14)22-17(25)12-6-5-11-9-13-18(26)20-7-4-8-24(13)16(11)21-12/h5-6,9-10H,4,7-8H2,1-3H3,(H,20,26)(H,22,23,25)
PDB
MMDB

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PC sid
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Similars

US Patent
n/an/a 19n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair