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BDBM168065 US9073926, 99

SMILES: C[C@H]1NC(=O)c2cc3ccc(nc3n2[C@H]1C)C(=O)Nc1cc(Cc2ccccc2)on1

InChI Key: InChIKey=KMZHUPNJAVFPRF-KGLIPLIRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168065   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (human))
BDBM168065
PNG
(US9073926, 99)
Show SMILES C[C@H]1NC(=O)c2cc3ccc(nc3n2[C@H]1C)C(=O)Nc1cc(Cc2ccccc2)on1
Show InChI InChI=1S/C23H21N5O3/c1-13-14(2)28-19(23(30)24-13)11-16-8-9-18(25-21(16)28)22(29)26-20-12-17(31-27-20)10-15-6-4-3-5-7-15/h3-9,11-14H,10H2,1-2H3,(H,24,30)(H,26,27,29)/t13-,14+/m1/s1
PDB
MMDB

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PC cid
PC sid
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Similars

n/an/a 5.10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair