BDBM168156 US9688642, 46
SMILES COc1ccc(F)c(c1)-c1ncc(COc2cccc(c2)[C@@H](CC(O)=O)C2CC2)nc1C1=CCCC1(C)C
InChI Key InChIKey=RPNNZNQBXGKPGZ-DEOSSOPVSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 168156
Affinity DataEC50: 128nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
Affinity DataEC50: 201nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Affinity DataEC50: 712nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair