BDBM17028 (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-5-hydroxy-2,3-dihydro-1H-indol-2-one::CHEMBL426078::Indolinone based inhibitor, 2f
SMILES Cc1cc(C)c(\C=C2/C(=O)Nc3ccc(O)cc23)[nH]1
InChI Key InChIKey=GUXYHZUGDWFOBA-GHXNOFRVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 17028
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of KDRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMpH: 7.2 T: 2°CAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair