BDBM17244 3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-5-methyl-4-[(4-methylpiperazin-1-yl)methyl]thiophene-2-carboxamide::thiophene-containing non-amidine inhibitor, 40

SMILES CN1CCN(Cc2c(C)sc(C(=O)Nc3ccc(Cl)cc3C(=O)Nc3ccc(Cl)cc3)c2Cl)CC1

InChI Key InChIKey=INKAAAVRNUCZBR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17244   

TargetCoagulation factor X(Homo sapiens (Human))
Berlex

LigandPNGBDBM17244(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi:  12nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex

LigandPNGBDBM17244(3-chloro-N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]...)
Affinity DataKi:  4.40E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed