BDBM172727 US9096515, 33a -(S)-Isomer::US9296681, 33a-(S)-Isomer

SMILES C[C@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=OZLLUGNMXJLQIE-CQSZACIVSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 172727   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172727(US9096515, 33a -(S)-Isomer | US9296681, 33a-(S)-Is...)
Affinity DataKi:  126nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172727(US9096515, 33a -(S)-Isomer | US9296681, 33a-(S)-Is...)
Affinity DataKi:  126nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172727(US9096515, 33a -(S)-Isomer | US9296681, 33a-(S)-Is...)
Affinity DataKi:  300nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172727(US9096515, 33a -(S)-Isomer | US9296681, 33a-(S)-Is...)
Affinity DataKi:  300nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172727(US9096515, 33a -(S)-Isomer | US9296681, 33a-(S)-Is...)
Affinity DataKi:  3.42E+3nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172727(US9096515, 33a -(S)-Isomer | US9296681, 33a-(S)-Is...)
Affinity DataKi:  3.42E+3nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In DepthDetails US Patent