BDBM173447 US9096601, 8-21

SMILES CC(C)n1c(Nc2ccc(NC(=O)Nc3ccc(F)c(Cl)c3)cc2)nc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc12

InChI Key InChIKey=OAZZXYMTTQCAGN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 173447   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM173447(US9096601, 8-21)
Affinity DataIC50:  11nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM173447(US9096601, 8-21)
Affinity DataIC50: >1.00E+3nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM173447(US9096601, 8-21)
Affinity DataIC50:  5nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM173447(US9096601, 8-21)
Affinity DataIC50:  5nMAssay Description:The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ...More data for this Ligand-Target Pair
In DepthDetails US Patent