BDBM173488 US9238653, Table 5, Compound 4

SMILES Cc1cc(Nc2ccc(Cl)cc2)n2nc(nc2n1)C(F)(F)F

InChI Key InChIKey=CMTZXCREJMUZHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173488   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173488(US9238653, Table 5, Compound 4)
Affinity DataIC50:  90nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent