BDBM174110 (S)-2-(3-(4-octylphenyl)-1,2,4- oxadiazol-5-yl)azetidine-1- carboximidamide

SMILES CCCCCCCCc1ccc(cc1)-c1noc(n1)[C@@H]1CCN1C(N)=N

InChI Key InChIKey=BCOGOUCOQHACIR-KRWDZBQOSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 174110   

TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM174110((S)-2-(3-(4-octylphenyl)-1,2,4- oxadiazol-5-yl)aze...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of recombinant human SphK2 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate after 20 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
University Of Virginia Patent Foundation

US Patent
LigandPNGBDBM174110((S)-2-(3-(4-octylphenyl)-1,2,4- oxadiazol-5-yl)aze...)
Affinity DataKi: >1.00E+4nMAssay Description:SphK activity was measured by a scintillation proximity assay as previously described [1], the disclosure of which is incorporated herein. Briefly, r...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine kinase 1(Homo sapiens (Human))
University Of Virginia Patent Foundation

US Patent
LigandPNGBDBM174110((S)-2-(3-(4-octylphenyl)-1,2,4- oxadiazol-5-yl)aze...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected sf9 cells using D-erythro-sphingosine as substrate after 20 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM174110((S)-2-(3-(4-octylphenyl)-1,2,4- oxadiazol-5-yl)aze...)
Affinity DataKi:  5.50E+4nMAssay Description:SphK activity was measured by a scintillation proximity assay as previously described [1], the disclosure of which is incorporated herein. Briefly, r...More data for this Ligand-Target Pair
In DepthDetails US Patent