BDBM174151 US9688669, Example 23

SMILES CCCC(C)C#Cc1cncc(c1)[C@H]1NC(=O)O[C@@H]1c1cccc(F)c1

InChI Key InChIKey=NPDNXFOYARHDTC-LZVFCHHLSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174151   

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM174151(US9688669, Example 23)
Affinity DataEC50:  44nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent