BDBM17453 1,2,3-triazole analogue, 9::5-(2-methoxyphenyl)-1H-1,2,3-triazole
SMILES COc1ccccc1-c1c[nH]nn1
InChI Key InChIKey=DXFUGJOFNXTOGO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 17453
Affinity DataKi: 150nM ΔG°: -9.21kcal/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human TDO transfected in mouse P815B clone 19 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Mus musculus)
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse TDO in P815 clone 12 cells by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+6nMAssay Description:Inhibition of human recombinant indoleamine-2,3-dioxygenase expressed in Escherichia coli BL21 using L-tryptophan as substrate after 30 mins by micro...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair