BDBM174937 US9096593, P-1669

SMILES COc1ncc(F)cc1CNc1ccc(Cc2c[nH]c3ncc(NC(C)=O)cc23)c(F)n1

InChI Key InChIKey=IWGLCABRVPLEJZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 174937   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM174937(US9096593, P-1669)
Affinity DataIC50: >1.00E+4nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM174937(US9096593, P-1669)
Affinity DataIC50: >1.00E+4nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM174937(US9096593, P-1669)
Affinity DataIC50:  5.00E+3nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM174937(US9096593, P-1669)
Affinity DataIC50: >1.00E+4nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM174937(US9096593, P-1669)
Affinity DataIC50: <5.00E+3nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
In DepthDetails US Patent