BDBM174965 US9096593, P-2003
SMILES Clc1cnc2[nH]cc(Cc3ccc(NCc4ccc(Cl)nc4)nc3)c2c1
InChI Key InChIKey=IHUPHYFSKVFFFO-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 174965
Affinity DataIC50: <100nMpH: 7.5 T: 2°CAssay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of Fms kinase activity, where inhibition of phosphorylati...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMpH: 7.5Assay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of c-Kit kinase activity, where inhibition of phosphoryla...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMpH: 7.5 T: 2°CAssay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of Flt-3 kinase activity, where inhibition of phosphoryla...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+3nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...More data for this Ligand-Target Pair