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BDBM176471 US9120752, 14

SMILES: Cc1noc(C)c1S(=O)(=O)N1CCN(CC1)C(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1

InChI Key: InChIKey=IUFQSVOPRWJQQJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176471   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176471
PNG
(US9120752, 14)
Show SMILES Cc1noc(C)c1S(=O)(=O)N1CCN(CC1)C(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C27H25FN4O5S/c1-18-26(19(2)37-30-18)38(34,35)32-16-14-31(15-17-32)27(33)25-5-3-4-24(29-25)20-6-10-22(11-7-20)36-23-12-8-21(28)9-13-23/h3-13H,14-17H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 220n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair