BDBM176491 US9688710, 72 (2S,3R,4R,5S,6R)-2-(3-(4-(2-aminoethoxy)benzyl)-4-chlorophenyl-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol

SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCCN)cc2)c1

InChI Key InChIKey=GKQAPNVIOUQZDP-CRSSMBPESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176491   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM176491(US9688710, 72 (2S,3R,4R,5S,6R)-2-(3-(4-(2-aminoeth...)
Affinity DataIC50: <10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 2 (SGLT2; accession number P31639; GI:400337) was cloned into pIRESpuro2 vector for mammalian expression (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM176491(US9688710, 72 (2S,3R,4R,5S,6R)-2-(3-(4-(2-aminoeth...)
Affinity DataIC50:  50nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent