BDBM176523 US9688710, 148 4-methyl-N-(2-(4-(2-methyl-5-((3R,4R,5S,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenoxy)ethyl)piperazine-1-carboxamide::US9688710, 88 N-(2-(4-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenoxy)ethyl)-4-methylpiperazine-1-carboxamide

SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C)c(Cc2ccc(OCCNC(=O)N3CCN(C)CC3)cc2)c1

InChI Key InChIKey=PMESPRUGJZUGPS-IONQDRQYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 176523   

TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM176523(US9688710, 148 4-methyl-N-(2-(4-(2-methyl-5-((3R,4...)
Affinity DataIC50: <10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM176523(US9688710, 148 4-methyl-N-(2-(4-(2-methyl-5-((3R,4...)
Affinity DataIC50: <10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 2 (SGLT2; accession number P31639; GI:400337) was cloned into pIRESpuro2 vector for mammalian expression (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM176523(US9688710, 148 4-methyl-N-(2-(4-(2-methyl-5-((3R,4...)
Affinity DataIC50: <10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM176523(US9688710, 148 4-methyl-N-(2-(4-(2-methyl-5-((3R,4...)
Affinity DataIC50: <10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 2 (SGLT2; accession number P31639; GI:400337) was cloned into pIRESpuro2 vector for mammalian expression (co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent