BDBM176561 US9120756, 23

SMILES C[C@H](C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key InChIKey=QSMNOKNPEPLVBN-LBPRGKRZSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 176561   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM176561(US9120756, 23)
Affinity DataKi:  0.300nM ΔG°:  -13.5kcal/moleT: 2°CAssay Description:The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM176561(US9120756, 23)
Affinity DataKi:  0.300nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Gruenenthal

US Patent
LigandPNGBDBM176561(US9120756, 23)
Affinity DataKi:  0.400nMAssay Description:The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM176561(US9120756, 23)
Affinity DataIC50:  47.1nMT: 2°CAssay Description:The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...More data for this Ligand-Target Pair
In DepthDetails US Patent