BDBM17663 (2S)-2-amino-3-(sulfooxy)propanoic acid::L-SOS::L-serine O-sulfate::Sulfoserine

SMILES: N[C@@H](COS(O)(=O)=O)C(O)=O

InChI Key: InChIKey=LFZGUGJDVUUGLK-REOHCLBHSA-N

Data: 1 KI  4 IC50

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 17663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-amino-N-butyrate transaminase (Sus scrofa)	BDBM17663 ((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...) Show SMILES N[C@@H](COS(O)(=O)=O)C(O)=O Show InChI InChI=1S/C3H7NO6S/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents	Article	2.40E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Apparent dissociation constants for inactivation of Gamma-amino-N-butyrate transaminase				Bioorg Med Chem Lett 2: 1371-1374 (1992)
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (HUMAN)	BDBM17663 ((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...) Show SMILES N[C@@H](COS(O)(=O)=O)C(O)=O Show InChI InChI=1S/C3H7NO6S/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009)
					More data for this Ligand-Target Pair
Cystine/glutamate transporter (Homo sapiens)	BDBM17663 ((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...) Show SMILES N[C@@H](COS(O)(=O)=O)C(O)=O Show InChI InChI=1S/C3H7NO6S/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of amino acid transport system xc-				Bioorg Med Chem Lett 20: 2680-3 (2010)
					More data for this Ligand-Target Pair
Glutamate Carboxypeptidase II (GCPII) (Homo sapiens (human))	BDBM17663 ((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...) Show SMILES N[C@@H](COS(O)(=O)=O)C(O)=O Show InChI InChI=1S/C3H7NO6S/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	4.38E+5	n/a	n/a	n/a	n/a	7.4	37
NCI-FCRDC					Assay Description The inhibition concentration values of GCPII were determined using the radioenzymatic assay with [3H] NAAG (radiolabeled on the terminal glutamate). ...				J Med Chem 50: 3267-73 (2007)
					More data for this Ligand-Target Pair				3D Structure (crystal)
Excitatory amino acid transporter 3 (HUMAN)	BDBM17663 ((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...) Show SMILES N[C@@H](COS(O)(=O)=O)C(O)=O Show InChI InChI=1S/C3H7NO6S/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009)
					More data for this Ligand-Target Pair