BDBM176766 US9675612, 10 2-Cyclobutyl-N-(1H-indazol-5-yl)[1,3]thiazolo[5,4-d]pyrimidin-7-amine

SMILES C1CC(C1)c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1

InChI Key InChIKey=DYAXDJBXKYCKQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176766   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM176766(US9675612, 10 2-Cyclobutyl-N-(1H-indazol-5-yl)[1,3...)
Affinity DataIC50:  54nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent