BDBM176814 US9675612, 47 N-[3-(Dimethylamino)-3-oxopropyl]-7-[(6-isopropoxy-1H-indazol-5-yl)amino]-N-methyl[1,3]thiazolo[5,4-d]pyrimidine-2-carboxamide

SMILES CC(C)Oc1cc2[nH]ncc2cc1Nc1ncnc2sc(nc12)C(=O)N(C)CCC(=O)N(C)C

InChI Key InChIKey=SLXIXSQVDODQRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176814   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM176814(US9675612, 47 N-[3-(Dimethylamino)-3-oxopropyl]-7-...)
Affinity DataIC50:  32nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent