BDBM177235 US9120749, 601::US9120749, 602

SMILES CC(C)(N)c1ccc(Nc2c(cnc3ccc(cc23)-c2cc(Cl)c(O)c(Cl)c2)C(=O)C2CC2)cc1

InChI Key InChIKey=RTPRYXVITUNRNN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177235   

TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Oncotherapy Science

US Patent
LigandPNGBDBM177235(US9120749, 601 | US9120749, 602)
Affinity DataIC50:  1.10nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Oncotherapy Science

US Patent
LigandPNGBDBM177235(US9120749, 601 | US9120749, 602)
Affinity DataIC50:  1.40nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In DepthDetails US Patent