BDBM177779 US10000475, Compound 8::US9120786, 8

SMILES FC(F)(F)c1ccc(Oc2ccc(cc2)-c2nc(nc(n2)N2CCOCC2)C#N)nc1

InChI Key InChIKey=NOVDRUURHFEDJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177779   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM177779(US10000475, Compound 8 | US9120786, 8)
Affinity DataIC50:  8.09E+3nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM177779(US10000475, Compound 8 | US9120786, 8)
Affinity DataIC50:  8.09E+3nMT: 2°CAssay Description:FLIPRTETRA Sodium Dye Assay with KCl: Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant o...More data for this Ligand-Target Pair
In DepthDetails US Patent