BDBM17781 CHEMBL65860::butane-1,2,4-tricarboxylic acid::carboxylate, 42

SMILES OC(=O)CCC(CC(O)=O)C(O)=O

InChI Key InChIKey=LOGBRYZYTBQBTB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17781   

TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17781(CHEMBL65860 | butane-1,2,4-tricarboxylic acid | ca...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Glutamate carboxypeptidase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2 [44-750](Homo sapiens (Human))
Mgi Pharma

LigandPNGBDBM17781(CHEMBL65860 | butane-1,2,4-tricarboxylic acid | ca...)
Affinity DataIC50:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed