BDBM178101 N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,2,3-triazol-4-yl)methyl)ethane-1,2-diamine (Compound 1)

SMILES CN(CCN)Cc1n[nH]nc1-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=KXMOTUWXUMLQRY-UHFFFAOYSA-N

Data  5 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 178101   

TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)
Affinity DataKi:  110nM IC50:  230nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)
Affinity DataKi:  1.50E+3nM IC50:  3.00E+3nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)
Affinity DataKi: >1.00E+4nM IC50: >2.00E+4nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)
Affinity DataKi: >3.75E+4nM IC50: >7.50E+4nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)
Affinity DataKi: >5.00E+4nM IC50: >1.00E+5nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed